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Gardening: It's Good For Your Health
Daily physical activity is a prerequisite for good health. Gardening is an excellent way to be physically active while growing healthy vegetables and fruits, as well as beautiful flowers. Active people are less likely than inactive people to be obese or have high blood pressure, type 2 diabetes, osteoporosis, coronary artery disease, stroke, depression, colon cancer and premature death. (Source: Cancercompass News: Breast Cancer)MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
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Colonic carcinoid tumors: a clinicopathologic study of 23 patients from a single institution
CONCLUSIONS: Carcinoid tumors of the colon are frequently right-sided and may be clinically occult until an advanced stage is reached. Based on the relatively poor survival rates reported, it is recommended that, in addition to standard surgical resection, vigorous surveillance for metastatic disease must be performed, particularly during the first 2 years after surgery. In addition, these patients require evaluation of the entire gastrointestinal tract for evidence of coexisting malignancy, along with an extended period of follow-up, because tumor recurrences after 5 years are not uncommon.CONTEXTO: Carcinóides cólicos, excluindo aqueles que se originam no apêndice cecal, são extremamente raros. Devido a esta raridade, as características e comportamento desta neoplasia permanecem ind...
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Identification of native Bacillus thuringiensis strain from South India having specific cytocidal activity against cancer cells
Conclusions: Our observations imply that B. thuringiensis LDC-391 is different from the already reported parasporin producers, as it is showing variation in the target specificity.Significance and Impact of the Study: Characterizing these proteins can pave the way to alleviate problems associated with neoplastic transformation and cancer progression. (Source: Journal of Applied Microbiology)
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Therapy Guidance for Patients with Colorectal Cancer Discussed at NCCN® Annual Conference
Highlights of the latest version of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines™) for Colon and Rectal Cancer were presented at the NCCN 15th Annual Conference by Paul F. Engstrom, MD, of Fox Chase Cancer Center. Engstrom discussed specific recommendations for therapies and provided guidance on patients who benefit most from select regimens.
March 11, 2010
HOLLYWOOD, FL — Despite statistics stating that colorectal cancer is the fourth most frequen... (Source: National Comprehensive Cancer Network)
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I Have Colon Polyps: Now What?
M. D. Anderson Cancer Center are encouraging men and women to learn more about colon polyps and how they affect a person's risks for cancer. "Finding out you have colon polyps doesn't have to be frightening," said Gottumukkala S. Raju, M.D., professor in the Department of Gastroenterology, Hepatology and Nutrition at M. D. Anderson. "Most colon polyps are not cancer... (Source: Public Health News From Medical News Today)MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
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I Have Colon Polyps: Now What?
M. D. Anderson Cancer Center are encouraging men and women to learn more about colon polyps and how they affect a person's risks for cancer. "Finding out you have colon polyps doesn't have to be frightening," said Gottumukkala S. Raju, M.D., professor in the Department of Gastroenterology, Hepatology and Nutrition at M. D. Anderson. "Most colon polyps are not cancer. Yet, certain kinds of polyps may make you more likely to develop colon cancer." The colon is part of the large intestine. A colon polyp is a growth on the inside lining of the colon... (Source: Health News from Medical News Today)
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Clinicopathological Features of Colon Polyps from African-Americans
Conclusion There was a ratio of 8:1 for neoplastic to hyperplastic polyps in our study, which is more than what has been reported in
Caucasians (7:1). Our data shows a shift in polyps from the left side to the right side of the colon in recent years. This
data is consistent with the lack of a reduction in the incidence of colon cancer in African-Americans. Screening is thus very
important in AA to reduce the incidence of colon cancer.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-010-1133-5Authors
Mehdi Nouraie, Howard University College of Medicine Department of Medicine and Cancer Center 2041 Georgia Avenue, N.W. Washington DC 20060 USAFatemeh Hosseinkhah, Howard University College of Medicine Department of Medicine and Cancer Center 204...
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Short-Term Outcomes of Laparoscopic Colectomy for Transverse Colon Cancer
Conclusions Laparoscopic resection for TCC can be performed safely with similar short-term postoperative outcomes seen for colon cancer
at other sites. Laparoscopic resection may be associated with faster gastrointestinal recovery and shorter length of hospital
stay, compared with open surgery.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s11605-010-1182-2Authors
Takashi Akiyoshi, Cancer Institute Hospital Gastroenterological Center, Department of Gastroenterological Surgery 3-10-6 Ariake, Koto-ku Tokyo 135-8550 JapanHiroya Kuroyanagi, Cancer Institute Hospital Gastroenterological Center, Department of Gastroenterological Surgery 3-10-6 Ariake, Koto-ku Tokyo 135-8550 JapanYoshiya Fujimoto, Cancer Institute Hospital Gastroenterological Center, Dep...
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Inhibition of TNFalpha-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-kappaB- and MAPK-dependent mechanisms.
In this study we show that TNFalpha, but not LPS, was significantly able to stimulate the production of NO in HSV-tk transduced 9L glioblastoma cell lines, mediated by the up-regulation of iNOS transcript and iNOS protein. The TNFalpha-induced up-regulation of iNOS expression was mediated by MAPK and NF-kappaB signaling pathways as revealed by using selective pharmaceutical inhibitors. A culture liquid extract of the edible and medicinal mushroom Marasmius oreades that was previously shown to inhibit iNOS expression in MCF-7 was utilized to prepare fractions and evaluate their ability to affect TNFalpha-induced iNOS expression in HSV tk transduced 9L cell lines. While most of the tested fractions were shown to inhibit TNFalpha-induced iNOS expression, they targeted different signaling path...
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Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo
In this study, we explored the specific role of mTORC2 in colon cancer using a short hairpin RNA expression system to silence the mTORC2-associated protein rictor. We found that downregulation of rictor in HT29 and LS174T colon cancer cells significantly reduced cell proliferation. Knockdown of rictor also resulted in a G1 arrest as observed by cell cycle analysis. We further observed that LS174T cells deficient for rictor failed to form tumors in a nude mice xenograft model. Taken together, these results show that the inhibition of mTORC2 reduces colon cancer cell proliferation in vitro and tumor xenograft formation in vivo. They also suggest that specifically targeting mTORC2 may provide a novel treatment strategy for colorectal cancer. (Source: Molecular Cancer)
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